Scopus ID: 7004910913
Dr. Canton started her academic career with a degree in Pharmaceutical Chemistry and Technology (summa cum Laude in 1991) followed by a PhD in Molecular and Cellular Biology and Pathology (1995). At the beginning of her career Prof. Canton’s research was focused on mitochondrial pathophysiology (supervisor Prof. Azzone) and subsequently centered on investigating the mechanisms underlying cardiac dysfunction (supervisor Prof. Di Lisa) focusing on identifying sources and targets of oxidative stress in the myocardium in pathologic conditions, highlighting a causal link between oxidation of myofibrillar proteins and contractile impairment. Her group then moved to the study of skeletal muscle, providing the rationale for a translational study of Monoamine Oxidase (MAO) inhibitors for treatment of muscular dystrophy. Dr. Canton is currently PI of the Monoamine oxidases in innate immunity laboratory at the Istituto di Ricerca Pediatrica, focusing on the role of MAO in the redox signalling in innate immune system.