Tissue Engineering

Research Activity

The group is born from the joint experience of applied biology and biomaterials engineering. Our group mainly studies skeletal muscle regeneration to develop new tissue engineering approaches for treating muscle diseases, defects and malformations. Examples of technical skills developed by our group are tissue decellularization and recellularization, 3D printing and bioprinting, 2D and 3D in vitro culture systems, design and fabrication of bioreactors for different tissue culture applications. Currently, our research is supported by project grants whose purpose is to regenerate in vitro different tissue engineered constructs as both in vitro models and in vivo tissue substitutes. Our experience ranges from the use of commercially available and clinically approved biomaterials to the production of extracellular matrix scaffolds, from the use of immortalized cell lines to the isolation of stem and progenitor cells from tissue biopsies, from the characterization of simple cell cultures to the functional analysis of 3D constructs obtained using bioreactors and in silico simulation of their mechanical properties.