Model Organisms Facility
Biomedical research is required, in specific cases, to use animal models to validate in vitro results. This has to be done according several regulations aimed at the protection of animals used for scientific purpose.
Animal Facility
Biomedical research is required, in specific cases, to use animal models to validate in vitro results. This has to be done according several regulations aimed at the protection of animals used for scientific purpose.
Facility manager Dr. Giuseppe Germano
The Model Organisms Facility at the IRP provides equipment and related technologies for the accommodation and maintaining of small animals (mice and zebrafish) for biomedical research according to international (Directive 63/2010/EU) and national (D.lgs. 26/2014) legislation concerning the protection of animals used for scientific purpose.
The Mouse facility is a specific pathogen-free (SPF) animal research unit that consists of one housing room with a total capacity of 320 individually ventilated cages, three experimental procedure rooms and one fully equipped behavioral testing room.
The Zebrafish facility consists of an automatic recirculating aquaria system with the capacity to house up to 2,000 zebrafish in 160 tanks and separate lab room equipped with a variety of instrumentation for microinjection and fluorescence imaging.
Dr. Giuseppe Germano
Scopus ID 56764354400
Dr. Giuseppe Germano is a Biologist and specialized in Clinical pathology. He obtained his PhD in Medicine of Development and Science Programming in 2007 from the University of Padua under the mentorship of Giuseppe Basso and trained at Children’s Hospital of Philadelphia (CHOP) as research visiting in the Carolyn Felix lab. His thesis explored the zebrafish as a model system for studying the MLL gene in normal hematopoiesis and leukemia. Currently, Dr. Germano is employed by Fondazione Istituto di Ricerca Pediatrica Città della Speranza (IRPCDS) since 2020.
He covers two positions, one as head of the Model Organisms Facility and member of the Animal Welfare Committee (OPBA) at IRPCDS, in accordance with Legislative Decree 26/2014, and the other one as Principal Investigator at the laboratory of Pediatric Hemato Oncology, where he deals diagnostic activities manly focused on the study of minimal residual disease (MRD) through the analysis of IG/TR gene rearrangements in patients affected by acute lymphoblastic leukemia enrolled at the Pediatric Hemato Oncology Clinic to the Department of Woman and Child Health, University of Padua.